• Clinical Trial Site

Expertise and resources for testing the psychopharmacological effects of drugs / compounds; including:

Understanding cognitive effects of new drugs

Driving simulator

Neurocognitive testing

• Computerised Mental Performance Assessment (COMPASS)
• Cognitive Drug Research (CDR)
• Swinburne University Computerised Cognitive Assessment Battery (SUCCAB), sensitive to the cognitive effects of ageing and interventions which reverse cognitive ageing
• Other tailored computerised /paper-and-pencil assessments

Stress and mood assessment

Standardised self-report measures, laboratory stressors and biomarkers (e.g. Autonomic Nervous System activity, cortisol)

Psychiatric assessment for depression, anxiety disorders, ADHD etc., and their response to specific nutraceutical and pharmaceutical interventions

Brain imaging techniques

Including:

• Functional Magnetic Resonance Imaging (fMRI)
• Magnetoencephalography (MEG)
• Electroencephalography (EEG)
• Transcranial Magnetic Stimulation (TMS)
• Near Infrared Spectroscopy (NIRS)

Other techniques assessing cognition-relevant biomarkers, including:

• Cardiovascular function
• Doppler ultrasound
• Flow-mediated dilatation(FMD)
• Arterial compliance
• Inflammation
• Oxidative stress
• Muscle Sympathetic Nerve Activity (MSNA)
• Blood pressure
• Baroreflex sensitivity (sympathetic and vagal)
• Plasma catecholamines
• Other specific biomarkers

Clinical Trials facilities at Sarawak campus, Malaysia

CHP conducts research at Sarawak, providing the capacity for single and dual-centre clinical trials examining effects of nutraceutical and other interventions on neurocognitive performance in different populations.